Disease: Radioulnar Synostosis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
WHCR Wolf-Hirschhorn syndrome chromosome region 0.638 0.577
SOS2 Q07890 SOS Ras/Rho guanine nucleotide exchange factor 2 Enzyme modulator 1.00 0.608 0.692
SOS1 Q07889 SOS Ras/Rac guanine nucleotide exchange factor 1 Enzyme modulator 1.00 0.485 0.808
SMC3 Q9UQE7 structural maintenance of chromosomes 3 1.00 0.535 0.846
SMC1A Q14683 structural maintenance of chromosomes 1A 1.00 0.509 0.808
SETD5 Q9C0A6 SET domain containing 5 1.00 0.560 0.731
RRAS P10301 RAS related Enzyme modulator 4.7E-03 0.543 0.808
RIT1 Q92963 Ras like without CAAX 1 Enzyme modulator 0.13 0.527 0.808
RASA2 Q15283 RAS p21 protein activator 2 Enzyme modulator 7.4E-31 0.579 0.769
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885
RAD21 O60216 RAD21 cohesin complex component 1.00 0.528 0.846
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
NSD2 O96028 nuclear receptor binding SET domain protein 2 Epigenetic regulator 1.00 0.507 0.769
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
NIPBL Q6KC79 NIPBL cohesin loading factor Nucleic acid binding 1.00 0.521 0.808
MRAS O14807 muscle RAS oncogene homolog Enzyme modulator 0.92 0.590 0.731
LZTR1 Q8N653 leucine zipper like transcription regulator 1 1.0E-92 0.547 0.808
LETM1 O95202 leucine zipper and EF-hand containing transmembrane protein 1 Transporter 1.2E-06 0.545 0.692
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885
KAT6B Q8WYB5 lysine acetyltransferase 6B Enzyme 1.00 0.525 0.731
HDAC8 Q9BY41 histone deacetylase 8 Epigenetic regulator 0.98 0.511 0.885
FGFRL1 Q8N441 fibroblast growth factor receptor like 1 Enzyme 1.2E-02 0.588 0.615
CTBP1 Q13363 C-terminal binding protein 1 Transcription factor 0.98 0.559 0.692
CPLX1 O14810 complexin 1 0.82 0.576 0.654